p70 s6 kinase การใช้

• Some phosphorylation of p70 S6 kinase was discovered.
• When BCAAs were administered following a training session, sufficient phosphorylation of p70 S6 kinase and S6 indicated activation of the signaling cascade.
• Infusion of leucine at rest produces a six hour stimulatory effect and increased protein synthesis by phosphorylation of p70 S6 kinase in skeletal muscles.
• TSC1 and TSC2 form a tumor suppressor complex that regulates phosphorylates p70 S6 kinase ( S6K1 ) and 4E-BP1 . mTOR forms two physically and functionally distinct multiprotein complexes : the rapamycin-sensitive mTORC1 and the rapamycin-insensitive mTORC2.